Advanced Complex Tissue Injury

The Complex Tissue Injury Program at St. Michael’s Hospital is a comprehensive multi-disciplinary program that includes clinical expertise, education, and research.

There are specialized outpatient Wound Care clinics along with inpatient teams divided into lower extremity, Wounds above the ankle, and ostomy. Patients come from all over Canada to be seen at the Wound Centre and we offer a pressure flap surgery program, high volume limb preservation group and the largest surgical HS program in the country.

The types of patients we seen in our Program include:

  • Congenital wounds such as Epidermolysis Bullosa (EB) and Hidradenitis Suppurativa (HS) offering some of the largest programs of their kind;
  • Acquired wounds such as pressure sores, diabetic foot ulcers, venous stasis ulcers, and various acquired injuries (trauma, surgery);
  • Limb preservation program;
  • Pressure sore flap surgery program.

Research involves both the development of novel diagnostic tools to assess wound healing and treatments to modulate the wound. We perform bench to bedside research and we are interested in knowledge translation to ensure our patients are receiving cutting edge care for their complex wounds.

Dr. Karen Cross MD PhD FRCSC sits on various national advisory boards for Wound Care. As an Associate Scientist at The Keenan Research Centre for Biomedical Science at St. Michael’s Hospital, Dr. Cross is completing various clinical trials on patients with wounds.

Learn more about EB (

Learn more about HS: (